Generic Name: Tramadol

Brand Names: ConZip, Ultram

Available Dose: Tramadol 50mg, 100mg, 200mg

Where to buy Tramadol online?



Tramadol, categorized as an opioid analgesic pill is widely used for treating acute, chronic and neuropathic pain. As like with other opioid analgesic medications, the working mechanism of the pill revolves around the central nervous system. Especially it impacts the brain and spinal cord. The active ingredient of this pill is hydrochloride which also happens to be its generic medication. Research indicates that individuals affected by acute and chronic pain prefer to buy genuine Tramadol in increased dosage strength so as to get relieved of pain at the earliest instance. This pill was first launched in Germany after which it came to sale in other countries in the western world. Fibromyalgia affected individuals can ease their pain by consuming this pain medication, as it found to be responsive to this kind of pain. Ultram is the another brand name through which the pill is popularly identified in the marketplace.

Reaction mechanism of Tramadol

Through rounds of research, it has been found that tramadol working potential is more or less identical to that of morphine. The medicinal component comprises of two racemic mixtures which enrich the healing potential of the medication. Indeed, these two isomers showcase high analgesic activity. Usually, physicians prescribe Ultram along with paracetamol pills as it amplifies the efficacy of this pain relief medication. It metabolites process is also identified to be highly powerful opioid belonging to the benzenoid class.

How Tramadol treats Neuropathic pain

Generally speaking, neuropathic pain is developed as a result of discrepancy in the signals encountered between nerve cells. The pain of this kind can only be controlled through opiate painkillers. People can take Ultram to treat their severe to chronic pain in an effective manner. It is known to offer relief from neuropathic pain by reducing the transmission that happens between nerve signals. Especially, Tramadol focuses on nerve signals that transmit pain sensation. Indeed, it increases the dopamine turnover that happens on µ-opioid receptors.

Actually speaking, the action of Ultram on µ-opioid receptors is very little, but then it is also perceived that there are other underlying mechanisms that can be attributed to its analgesic effect. The analgesic effect it causes while treating neuropathic pain is because of the impact it causes on epinephrine and serotonin. It is supposedly perceived that persons who are taking this pain relief pill experience elevated pleasure and mood levels, and this is because of the impact it causes on the serotonin levels. For treating neuropathic pain, the maximum dose of Tramadol should be taken in the evening time.

How long does it take to achieve peak plasma

It is available in various forms like tablets, capsules, injections and extended-release formulations. Upon consuming tramadol, the analgesic effects can be experienced in an hour’s time, whereas the time taken to achieve peak plasma concentration in blood levels falls in the range between 2-4 hours. People with acute pain can take Tramadol in the appropriate dosage strength so as to experience the effects equivalent to that of morphine. It takes approximately 3 hours for the pain killing effects to achieve its peak.

How long does the effect of the drug last in the body?

However, these pain relief effects last for a longer period of time in the body compared to other pain killer pills. It is estimated that the pain relieving effects linger in the body for about 6 hours of time. The general observation is that by consuming tramadol on a daily basis one can gain about one tenth of the potency of morphine.

What are medical properties?

Certain medical properties of Tramadol are identical to that of antidepressant medications. One such property is that it binds to specific mu receptors in the body which are opioid in nature and the second property of this pain relief is that it blocks the reuptake of serotonin and norepinephrine. These are the two brain chemicals responsible for transmitting messages between nerve cells.

What are the dosage levels for different problems?

It is available in the dosage strength of 50 mg, 100 mg, 200 mg and 300 mg. For severe chronic pain, take extended-release tablets with the dosage strength of 100 mg initially and you may increase it to the maximum of 300 mg at a later point of the treatment. For mild chronic pain, take tramadol medication with the dosage strength of 25 mg per day initially and which can be increased up to the maximum dosage strength of 100 mg. pediatric patients would be prescribed with the lowest dosage strength. The dosage strength would vary according to the medical ailment, severity and age.

What are the precautions to be kept in mind?

  • Never break the extended-release capsules, as it would cause serious health hazards.
  • A pregnant and lactating woman should not take the medication.
  • Alcohol should not be taken while taking tramadol medication.
  • Do not misuse it at any point of time as it would lead to drug addiction.
  • Avoid sharing pills with others especially those who have a history of drug abuse.
  • Consult with the doctor regarding your health condition and take this pain relief medication.
  • Avoid taking drugs that might interact with the medication.

What are the side effects caused by taking the drug?

Side effects that are caused by taking tramadol are:

Minor side effects:

  • Dizziness
  • Feeling very tired
  • Drowsiness
  • Constipation
  • Headache
  • Nausea
  • Diarrhea
  • Sweating
  • Vomiting
  • Stomach pain
  • Flushing
  • Itching
  • Nervousness
  • Anxiousness

Major side effects:

  • Convulsions or seizures
  • Infertility
  • Missed menstrual periods
  • Shallow breathing
  • Impotency
  • Loss of interest in sex
  • Low cortisol levels
  • Severe skin reactions
  • Sore throat
  • Swelling in your face or tongue
  • Burning in the eyes
  • Blistering

Get medical help from a health care professional if in case the ill effect lasts for a longer period. Follow the instructions of the doctor carefully in such cases.



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